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Application of pre－and post－surgical planning in neurosurgery employing fMRI
黄仲奎 龙莉铃 张筱双
530021 南宁，广西医科大学第一附属医院放射科
zhong－kui，Long li－ling，Zhang xiao－shuang. Department of Radiology，The Ffirst Affiliated Hospital，Guangxi Medical University，Nanning，530021 China
Abstract
Objective：To investigate clinical usefulness of intracranial lesions in pre－and post－operation by functional MRI with blood oxygen level dependent（BOLD）technique.
Methods：Common MRI and Motor hand area functional MRI examinations were performed in 45 patients （fMRI group）with intracranial lesions adjacent to the motor cortex before and after operation. As contrast group，20 patients with occupying position lesions were made a routine MRI examination without fMRI before surgery. A 1.5T signa super conducting system was employment （GE company ，America）.
Results：The focal transactivation domain of cerebration was seen on fMRI in all cases of fMRI group. The cortical motor hand area shown displacement in 22 cases with abnormal size and shape and found not displacement in 23 cases. The distribution of transactivation domain was not changed in different disease . There was positive correlation between the distance from lesions to the domains and myodynamia in preoperation（r＝0.553，P<0.001），but none in post－operation（r＝0.059，P>0.05）. Our data indicated that there was negative correlation between the distance and the difference of myodynamia （r＝－0.570，P<0.001）. After operation，the size of cortical motor hand domain increased in 19 cases with different degree compared to pre－operation，no myodynamia decrease was found after operation. In the contrast group，myodynamia decreased in 25％ of cases. The average values of differences in myodynamia pre－ and postoperatively in fMRI group and control group were relatively 0.31±0.47 and －0.05±0.069，there were significant difference between the two average values（t＝2.473，P＝0.016）. | 
