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本研究目的是确定子宫内膜癌的MRI分期指南。
由欧洲泌尿生殖放射学会女性生殖系统分会组织，对欧洲10所医学院与1999年至2008年期间发表的文献中关于子宫内膜癌MRI参数进行评议取得专家一致意见。结果标明：高场强MRI至少应该包括盆腔内器官的矢状面、斜横断面或斜冠状面（子宫体的长、短横断面）的2个T2加权序列。
建议在静脉注射对比剂2 min +/- 30 s后采集高分辨增强影像以优化子宫肌层受侵犯的诊断。如果怀疑宫颈侵犯，推荐加做垂直于宫颈管长轴的的断面影像。
鉴于不用淋巴结特异性对比剂进行MRI对淋巴结检出敏感性低，最好行上至肾脏水平的平扫对腹膜后淋巴结进行筛查。子宫内膜取样显示组织学高分级与MRI监测子宫肌层及宫颈侵犯，提示淋巴结受侵的可能性较大，需要分期淋巴结切除。总之，通过专家一致意见及文献综述形成了子宫内膜癌分期的优化MRI扫描参数。
Staging of endometrial cancer with MRI: guidelines of the European Society of Urogenital Imaging.
The purpose of this study was to define guidelines for endometrial cancer staging with MRI. The technique included critical review and expert consensus of MRI protocols by the female imaging subcommittee of the European Society of Urogenital Radiology, from ten European institutions, and published literature between 1999 and 2008. The results indicated that high field MRI should include at least two T2-weighted sequences in sagittal, axial oblique or coronal oblique orientation (short and long axis of the uterine body) of the pelvic content. High-resolution post-contrast images acquired at 2 min +/- 30 s after intravenous contrast injection are suggested to be optimal for the diagnosis of myometrial invasion. If cervical invasion is suspected, additional slice orientation perpendicular to the axis of the endocervical channel is recommended. Due to the limited sensitivity of MRI to detect lymph node metastasis without lymph node-specific contrast agents, retroperitoneal lymph node screening with pre-contrast sequences up to the level of the kidneys is optional. The likelihood of lymph node invasion and the need for staging lymphadenectomy are also indicated by high-grade histology at endometrial tissue sampling and by deep myometrial or cervical invasion detected by MRI. In conclusion, expert consensus and literature review lead to an optimized MRI protocol to stage endometrial cancer.
本文英文原文源于：Kinkel K, Forstner R, Danza FM, Oleaga L, Cunha TM, Bergman A, Barentsz JO, Balleyguier C, Brkljacic B, Spencer JA.Eur Radiol. 2009 Jul;19(7):1565-74.
文章来自：影像园
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