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Preliminary Evaluation of 1 HMR Spectroscopy in Studying Bone and Soft Tissue Diseases of the Lower Limbs<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />
周春香 孟悛非 陈应明 罗柏宁 张中伟
Chun－xiang ZHOU, Quan－fei MENG, Ying－ming CHEN,et al .Department of Radiology, No. 1 Affiliated Hospital, Sun Yat－sen University,Guangzhou,Guangdong Province 510080, P. R. China
Abstract
Objective：To discuss the feasibility and the clinical value of 1HMR spectroscopy (MRS) in studying bone and soft tissue diseases of the lower limbs.
Materials and Methods：1HMRSwas performed to study the lower limbs. The lower limbs of the subjects had normal skeleton ( n = 10) , normal muscles ( n = 5) , benign lesions ( n = 6) , malignant bone tumor ( n = 11) or rhabdomyosarcoma ( n = 1) . SVS－STEAM sequence was used.
Results：1H MRS wave style of the diseased bone and soft－tissue was different from that of the normal ones , and the difference also existed between benign and malignant lesions. Choline level in malignant lesions was markedly higher than that in benign lesions.
Conclusion：1H MRS is an ideal and noninvasive means for the study of biochemical and metabolic characteristics of bone and soft2tissue disorders of the limbs.
Key words：Limb；Bone；Soft－tissue；1H MRS | 
